MENOPAUSE DISEASE AND BLADDER NECK SCLEROSIS
				
				
				 by 
				Georges Debled MD.
		
					
					G. Debled. The 
					menopause disease.
					Approaches 
					to aging control : 19:17-24,October 
					2015
					
					
					The menopause 
					disease .pdf  					 					 
					
					Octobre 2015.   
					SEMAL Madrid
			
			
			
				
				
			Aging of sexual organs and 
				its treatment
				
				solution is
				here
				
			
					
			
			
			
					
					
					SCLEROSIS AND INFLAMMATION OF BLADDER NECK
					
					Incontinence, urgencies, chronic cystitis and 
					devastating disorder of interstitial cystitis can be the 
					consequences of a bladder neck sclerosis and inflammation 
					(see drawings)
					
					Numerous bladder neck scleroses in women are the 
					consequences of androgens’ deficiencies (mainly 
					dihydrotestosterone) before menopause (oral contraceptive) 
					or after menopause (menopause disease: see above).
					
					Those bladder neck consequences (Incontinence, 
					urgencies, chronic cystitis and devastating disorder of 
					interstitial cystitis) due to androgens’ deficiencies may 
					improve with mesterolone. Results can be spectacular.
					
					As urologist Georges Debled MD. has an experience 
					about bladder neck sclerosis (and its endoscopic surgery) in 
					woman since 40 years. The last 10 years he discovered the 
					role of dihydrotestosterone on the woman’s bladder neck and 
					the benefit effect of mesterolone on this pathology.
					
					There exists no description of 
					mesterolone effect on bladder neck in the world literature. 
					Those findings are disclosed here for the first time. 
					
				
				
				URETHRA AND BLADDER NECK IN WOMAN
			
				
				
				
			
				
				 The urethra 
				
				is constituted from 3 
				parts approximately  
				from same length  
				(1 
				centimeter in adult woman) :
				
				
				
				
				
				
				The inner part is constituted by a fibromuscular tissue in 
				continuity with the fibromuscular tissue of the bladder (bladder 
				neck). 
				It is the homologue of the prostate in men. For a detailed 
				description of the female prostate, please click 
				here.
			
				
			
			
				
				The medium part is constituted by the sphincter.
			
				
				
			
			
										
				
				
				The external part is a conduct.
				
				
				The bladder neck is known in the medical literature, even in 
				medical books of great value, as the inner sphincter. As a 
				sphincter is a muscular structure contracted around a natural 
				orifice (red arrows) the bladder neck is not a sphincter. 
				Surrounding a natural orifice, it is not contracted and
				
				
				its contraction leads to the opening
				of its natural orifice on the contrary of a sphincter! 
				( is the homologue of the prostate in men).
				
				
				Fibrosis of the bladder neck can be congenital but a great 
				number of cases are acquired during life.
				
				When opening (green arrows) the 
				bladder neck  
				doesn’t open well 
				and its maximum diameter is often less than 1 centimeter.
			
				
				
					
						
							| 
							 
							  
							
							
							Bladder neck sclerosis (in green) with narrowing of 
							the urethra 
							 | 
							
							 
							  
							
							
							Bladder neck sclerosis (in green) without narrowing 
							of the urethra 
							 | 
							
							 
							  
							
							
							Moderate bladder neck sclerosis (striated in green) 
							without narrowing of the urethra 
							 | 
						
					
				 
				
				
				
				 
				
				
				BLADDER NECK SCLEROSIS CONGESTION AND INFLAMATION IN WOMAN
				
				
				 
				
					
						
							| 
							 
							  
							
							
							Bladder neck sclerosis with congestion 
							 | 
							
							 
							  
							
							
							Endoscopy of bladder neck sclerosis with congestion 
							 | 
						
						
							| 
							 
							
							
							
							  
							
							
							 Bladder neck 
							sclerosis with inflammation and inflammatory polyps 
							 | 
							
							 
							
							
							
							  
							
							
							Endoscopy of bladder neck sclerosis
							 with 
							inflammatory polyps 
							 | 
						
					
				 
				
				
				
				INCIDE                   
				
				
			
			
				
				Venous dilatations make the bladder neck congestive with and 
				abnormal sensitivity.NCE OF ADROGENS’DEFICIENCY ON WOMAN’S BLADDER NECK
			
				
				Mesterolone only treatment has cured spectacularly a woman withh
				
				 bladder neck was congestive with abnormal sensitivity. Urologist 
				of this womann  had 
				proposed an endoscopic surgery which was postponed thanks the 
				mesterolone treatment . This woman is free of symptoms sincee
				
				
				more than 10 
				yearss.
			
				
			
				
				
				ANATOMOPATHOLOGY OF BLADDER NECK SCLEROSIS IN WOMAN
				
					
						
							| 
							 
							
							
							
							  
							
							
							Important sclerosis of bladder neck in woman 
							 | 
							
							 
							
							
							
							  
							
							
							
							Normal musculature (in red) of bladder neck. 
							 | 
							
							 
							
							
							
							  
							
							
							Sclerosis of bladder neck   
							
							
							(in green).  
							
							 
							 | 
						
					
				 
				
				 
					
				
				
				MECHANICAL
					CONSEQUENCES OF A BLADDER NECK SCLEROSIS
				
					
						| 
						 
						  
						
						
						Hypertrophy of bladder musculature 
						
						
						  
						 | 
						
						 
						  
						
						
						Hypertension in upper urinary tract 
						
						
						  
						 | 
					
					
						| 
						 
						
						Weak bladder musculature 
						
						
						  
						 | 
						
						 
						
						Bad function of kidneys (which are under pressure) 
						 | 
					
				
				
				
				 
				
				
				
				
				
				
				How to know if the is an hypertension in the upper urinary tract 
				?
					
					
					
				EVOLUTION OF LOWER URINARY TRACT INFECTION
				
				
				
				AFTER REMOVING
				OF BLADDER NECK SCLEROSIS IN WOMAN
			
			
			
				
					| 
					
					 
					
					
					
					  
					
			
					
					
					  Immediately 
					after bladder neck resection of fibrous tissue inflammation 
					tissue may remains in the bladder wall or in anterior 
					urethra.
					
			
			
					
			
			
					 | 
			
			
					
					
					 
					
					
					
					  
					
					
					Immediately after bladder neck resection of fibrous 
					tissue inflammation tissue may remains in anterior urethra. 
					 | 
					
					
					 
					
					
					
					  
					
					
					
					After bladder neck resection of fibrous tissue inflammation 
					disappears generally completely within 3 months. 
					 | 
				
			
			
			
			
								
			
			
				
					| 
					   
					
					
					Before bladder neck resection of fibrous tissue when opening 
					the bladder neck doesn’t open well 
					
					(see above) 
					
					and its maximum diameter 
					is often less than 1 centimeter. 
					
						 
					 | 
				
				
					| 
					 
					
					
					
					  
					
					
					Bladder neck after resection of fibrous tissue : right 
					 | 
					
					 
					
					
					
					  
					
					
					Bladder neck after resection of fibrous tissue : left 
					 |